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Scaffold-free Tissue
Corneal Equivalent Tissue

Cutting-edge bioengineered tissue is designed to mimic the natural environment of the human body, providing an optimal platform for cellular activities.

Our patented process lets cells create their own natural structure, improving function and compatibility with existing processes.

Corneal Equivalent Tissue

Cutting-edge bioengineered tissue is designed to mimic the natural environment of the human body, providing an optimal platform for cellular activities.

Our patented process lets cells create their own natural structure, improving function and compatibility with existing processes.

Ocular Toxicity Testing

One application for our corneal-equivalent tissue technology is the development of KeratoxTM, an ocular toxicity testing platform that offers innovative companies an in-house, high-throughput testing solution that provides early indications of the ocular toxicity profile of novel compounds, and reduces the reliance on animal testing in demonstrating product safety within the R&D process.


Man in lab using Keratox to evaluate ocular toxicity profile of chemical formulations.

Research Student Enrico C. Torre in the lab using KeratoxR during Innovate UK supported proof of concept project


Sarah Greenhalgh, Managing Director of Kerato, commented:
"Kerato's Ocular Toxicity Testing Platform will be transformative, offering a new testing method that can be seamlessly implemented within existing R&D pathways and scaled, helping to meet the growing global demand for alternative and sustainable processes." 


Ocular Toxicity testing is a regulatory requirement for all new-to-market pharmaceutical and consumer goods products to ensure ensure compliance with safety standards. The United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN-GHS) classifies chemicals based on their potential to cause adverse effects on human health and the environment.

KeratoxTM Benefits


High throughput in-vitro test

KeratoxTM will provide innovative R&D focused chemical and pharmaceutical companies with an in-house, high-throughput in-vitro test that can be used to evaluate the ocular toxicology of known and novel chemical formulations.

Providing early indications of a formulationsโ€™ ocular toxicity profile with reference to UN-GHS, distinguishing between Class I, Class IIa and IIb, and unclassified chemicals.

Reduction in late-stage test fail burden, providing savings to companies

Our product aligns with international policies aimed at reducing the reliance on animal testing and addresses shortfalls in currently available testing solutions


Timeline

2024 - Collaborative Accelerated Knowledge Transfer Project with Newcastle University and 3D Bio-Tissues supported by Innovate UK provided early proof of concept data.

Want to learn more about what we do, and how we could work with your business or research group? Get in touch!
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